Description

2,3,5-Trifluoro-4-trifluoromethyl-phenylamine is a high-purity fluorinated aniline derivative, a critical building block in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the trifluoromethyl and fluorine substituents, which are essential for modifying the biological activity and physical characteristics of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials like liquid crystals and electronic chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs).
• Electronic Chemicals: Employed in the synthesis of specialty monomers and polymers for dielectric materials, semiconductors, and other electronic applications.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for heterocyclic compounds in various fine chemical processes.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing novel fluorinated dyes and pigments with enhanced lightfastness and chemical resistance.

Basic Information

Product Name	2,3,5-Trifluoro-4-trifluoromethyl-phenylamine
CAS No.	123950-43-6
Molecular Formula	C7H3F6N
Molecular Weight	215.10 g/mol
Synonyms	2,3,5-Trifluoro-4-(trifluoromethyl)aniline; 4-Amino-2,3,5-trifluorobenzotrifluoride; 2,3,5-Trifluoro-α,α,α-trifluoro-p-toluidine; 2,3,5-Trifluoro-4-trifluoromethylbenzenamine; 2,3,5-Trifluoro-4-(trifluoromethyl)phenylamine; 4-(Trifluoromethyl)-2,3,5-trifluoroaniline; Benzenamine, 2,3,5-trifluoro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2,3,5-Trifluoro-4-trifluoromethyl-phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.