Description

8-Bromo-6-(Dimethylamino)-9-(3-Formamidobenzyl)-9H-Purine is a high-purity, functionalized purine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel pharmaceutical agents and biochemical probes. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel adenosine receptor modulators and kinase inhibitors for drug discovery programs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D.
• Biochemical Probe Development: Used to create labeled or modified purine analogs for studying enzyme mechanisms and cellular signaling pathways.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and further functionalization to create complex heterocyclic libraries.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of active pharmaceutical ingredients (APIs) at various development stages.

Basic Information

Product Name	8-Bromo-6-(Dimethylamino)-9-(3-Formamidobenzyl)-9H-Purine
CAS No.	123811-36-9
Molecular Formula	C15H15BrN6O
Molecular Weight	375.23 g/mol
Synonyms	9-[(3-Formamidophenyl)methyl]-8-bromo-6-(dimethylamino)-9H-purine; 8-Bromo-6-dimethylamino-9-(3-formamidobenzyl)purine; 8-Bromo-6-(dimethylamino)-9-[(3-formamidophenyl)methyl]-9H-purine; 8-Bromo-9-(3-formamidobenzyl)-6-(dimethylamino)purine; 123811-36-9; 6-(Dimethylamino)-8-bromo-9-(3-formamidobenzyl)purine
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-(Dimethylamino)-9-(3-Formamidobenzyl)-9H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.