Description

3-Fluoro-4-Methoxybenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electron-donating methoxy group and a fluorine atom, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifiers: Incorporated into specialty polymers to alter thermal stability, solubility, and chemical resistance.
• Complex Ligand Synthesis: Utilized in organometallic chemistry for creating novel ligands used in catalysis.
• Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-Fluoro-4-Methoxybenzylamine
CAS No.	123652-95-9
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	(3-Fluoro-4-methoxyphenyl)methanamine; 4-Methoxy-3-fluorobenzylamine; 1-(Aminomethyl)-2-fluoro-4-methoxybenzene; 3-Fluoro-4-methoxybenzenemethanamine; 3-Fluoro-p-anisylamine; 3-Fluoro-4-methoxybenzyl amine; α-Amino-3-fluoro-4-methoxytoluene; Benzenemethanamine, 3-fluoro-4-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxybenzylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.