Description

Ethyl 4-(4-Hydroxyphenyl)-6-Methyl-2-Oxo-3,4-Dihydro-1H-Pyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyrimidinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel dihydropyrimidinone-based drugs, which are explored for a wide range of biological activities.
• API Synthesis: Serves as a core scaffold for the development of potential Active Pharmaceutical Ingredients (APIs) targeting cardiovascular, anti-inflammatory, and antimicrobial applications.
• Agrochemical Research: Used in research and development of new agrochemicals, including herbicides and fungicides, leveraging its heterocyclic structure.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing more complex molecular architectures in academic and industrial R&D settings.
• Material Science Research: Investigated as a monomer or additive for creating novel polymers and functional materials with specific optical or electronic properties.

Basic Information

Product Name	Ethyl 4-(4-Hydroxyphenyl)-6-Methyl-2-Oxo-3,4-Dihydro-1H-Pyrimidine-5-Carboxylate
CAS No.	123629-41-4
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	Ethyl 4-(4-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbethoxy-4-(4-hydroxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 4-(4-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic Acid Ethyl Ester; DHPM Derivative; Biginelli Reaction Product; Dihydropyrimidinone Derivative
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4-Hydroxyphenyl)-6-Methyl-2-Oxo-3,4-Dihydro-1H-Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.