Description

Boc-Cys(Tacm)-Oh Cha is a protected cysteine derivative, specifically designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain reactivity during the construction of complex peptides and proteins. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the development of peptide-based therapeutics and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of cysteine residues with orthogonal side-chain protection.
• Peptide Drug Discovery: Used in the research and development of novel therapeutic peptides, including hormone analogs and enzyme inhibitors.
• Conjugation & Bioconjugation: Enables site-specific modification of peptides and proteins for creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Disulfide Bond Formation Studies: Facilitates the study and controlled formation of disulfide bridges, which are crucial for protein folding and stability.
• Chemical Biology Research: Serves as a specialized reagent for probing protein structure-function relationships and enzyme mechanisms.
• Custom Peptide Manufacturing: An essential intermediate for contract research and manufacturing organizations (CROs/CMOs) producing high-purity custom peptides.

Basic Information

Product Name	Boc-Cys(Tacm)-Oh Cha
CAS No.	123577-65-1
Molecular Formula	C15H26N2O5S2
Molecular Weight	378.51 g/mol
Synonyms	Boc-Cys(Tacm)-OH; N-α-Boc-S-Tacm-L-cysteine; tert-Butyloxycarbonyl-S-(trimethylacetamidomethyl)cysteine; Boc-S-(trimethylacetamidomethyl)-L-cysteine; Boc-Cys(Tacm)-OH·CHA; Cyclohexylamine salt of Boc-Cys(Tacm)-OH; (2R)-2-[(tert-Butoxycarbonyl)amino]-3-[[[2,2-dimethylpropanoyl]amino]methyl]sulfanyl]propanoic acid cyclohexylamine salt
EINECS	Contact for details

Quality Control

Our Boc-Cys(Tacm)-Oh Cha is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements, including those for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation	-20.0° to -24.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.