Description

4-Fluoro-2-(Trifluoromethoxy)Aniline, 97% is a high-purity fluorinated aniline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoromethoxy and fluorine substituents, which impart desirable properties like metabolic stability and lipophilicity to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for enhanced bioactivity and pharmacokinetics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group improves efficacy and environmental profile.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials due to its electron-withdrawing characteristics.
• Dye and Pigment Manufacturing: Acts as a starting material for synthesizing novel fluorinated dyes and pigments with superior lightfastness and chemical resistance.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethoxy)Aniline, 97%
CAS No.	123572-66-7
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	4-Fluoro-2-(trifluoromethoxy)benzenamine; 2-Amino-5-fluoroanisole, 2-Trifluoromethoxy-4-fluoroaniline; 4-Fluoro-α,α,α-trifluoro-o-anisidine; 1-Amino-4-fluoro-2-(trifluoromethoxy)benzene; Benzenamine, 4-fluoro-2-(trifluoromethoxy)-; 4-Fluoro-2-trifluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethoxy)Aniline, 97% is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the declared purity and impurity profile specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.