Description

5-Fluoro-2-(trifluoromethoxy)aniline, 97% is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoromethoxy and fluorine substituents, which are instrumental in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, such as Buchwald-Hartwig amination or Suzuki reactions, to introduce complex aniline motifs.

Basic Information

Product Name	5-Fluoro-2-(trifluoromethoxy)aniline, 97%
CAS No.	123572-63-4
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	2-Amino-4-fluoro-1-(trifluoromethoxy)benzene; 4-Fluoro-2-(trifluoromethoxy)aniline; 5-Fluoro-2-(trifluoromethoxy)benzenamine; 2-(Trifluoromethoxy)-5-fluoroaniline; 5-Fluoro-α,α,α-trifluoro-o-anisidine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(trifluoromethoxy)aniline, 97% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the declared purity and impurity profile specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent content is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.