Description

2,4-Difluoro-5-(Trifluoromethoxy)Benzenamine is a high-value fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to create novel active ingredients with improved performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, central nervous system (CNS), and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to potency and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Functional Material Development: Employed in creating specialty polymers, dyes, and organic electronic materials requiring specific electronic and steric properties.
• Chemical Research & Development: A versatile reagent for introducing the difluoro-(trifluoromethoxy)aniline moiety into complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	2,4-Difluoro-5-(Trifluoromethoxy)Benzenamine
CAS No.	123572-59-8
Molecular Formula	C7H4F5NO
Molecular Weight	213.11 g/mol
Synonyms	5-Amino-1,3-difluoro-2-(trifluoromethoxy)benzene; 2,4-Difluoro-5-(trifluoromethoxy)aniline; 2,4-Difluoro-5-(trifluoromethoxy)phenylamine; 5-(Trifluoromethoxy)-2,4-difluoroaniline; Benzenamine, 2,4-difluoro-5-(trifluoromethoxy)-; 2,4-Difluoro-α,α,α-trifluoro-m-anisidine
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-(Trifluoromethoxy)Benzenamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.