Description

2-Fluoro-4-(Trifluoromethoxy)Aniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethoxy and fluorine substituents make it a valuable intermediate for creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This specialty chemical is essential for research and development teams in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Functional Material Development: Building block for advanced polymers, dyes, and electronic chemicals requiring specific electronic and steric properties.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D in cross-coupling reactions, amide formation, and heterocycle construction.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethoxy)Aniline
CAS No.	123572-58-7
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	2-Fluoro-4-(trifluoromethoxy)benzenamine; 4-Amino-3-fluoro-1-(trifluoromethoxy)benzene; 3-Fluoro-4-aminophenyl trifluoromethyl ether; Benzenamine, 2-fluoro-4-(trifluoromethoxy)-; 2-Fluoro-4-trifluoromethoxyaniline; 2-F-A-TFMOA; 2-F-4-TFMOA
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Trifluoromethoxy)Aniline is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards and provide comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (Typical 99.0%)
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.