Description

3-Mercaptopropionyl-Tyr-D-Trp-Lys-Val-Cys-p-Chloro-D-Phe-Nh2, (Disulfide Bond Between Deamino-Cys1 And Cys6) is a synthetic peptide analog of somatostatin, featuring a constrained cyclic structure formed by a disulfide bridge. This compound is of significant interest for its potent biological activity and high receptor binding affinity, making it a valuable tool in biochemical research and pharmaceutical development. It is primarily utilized by researchers and developers in the fields of endocrinology, oncology, and neurobiology for studying hormone regulation, tumor growth inhibition, and as a lead compound for novel therapeutic agents.

Application

• Biomedical Research: As a reference standard and active probe in somatostatin receptor (SSTR) binding studies and signal transduction research.
• Pharmaceutical Development: Serving as a key intermediate or lead compound in the design of novel peptide-based therapeutics targeting neuroendocrine tumors and acromegaly.
• In Vitro Diagnostics: Used in the development of competitive immunoassays and other diagnostic kits for hormone-related disorders.
• Academic Research: Fundamental studies in peptide chemistry, structure-activity relationships (SAR), and metabolic pathways.
• Preclinical Studies: Evaluation of pharmacokinetics, biodistribution, and efficacy in animal models for potential drug candidates.

Basic Information

Product Name	3-Mercaptopropionyl-Tyr-D-Trp-Lys-Val-Cys-p-Chloro-D-Phe-Nh2, (Disulfide Bond Between Deamino-Cys1 And Cys6)
CAS No.	123528-93-8
Molecular Formula	C53H68ClN11O10S2
Molecular Weight	1122.74 g/mol
Synonyms	Deamino-Cys1, Cys6 Disulfide Cyclic Somatostatin Analog; 3-Mercaptopropionyl-[Tyr-D-Trp-Lys-Val-Cys-p-Chloro-D-Phe]-NH2 (cyclic 1-6 disulfide); Somatostatin Analog (cyclic, 1-6 disulfide); BIM-23014 (CGP 23996 analog); Cyclic Somatostatin Octapeptide Analog; [Deamino-Cys1, p-Cl-D-Phe6, Cys14]-Somatostatin; 3-MP-Somatostatin Analog
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing purity, amino acid analysis, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under desiccant. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak confirmed
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.