Description

4,5-Difluoro-o-phenylenediamine dihydrochloride is a high-purity, halogenated aromatic diamine salt serving as a critical synthetic intermediate. This compound matters for its role in constructing complex heterocyclic scaffolds, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and functional dyes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated benzimidazole and quinoxaline derivatives, which are core structures in various drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the difluoro substitution pattern can enhance biological activity and environmental stability.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for the production of high-performance polyimides and other specialty polymers with enhanced thermal and chemical resistance.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of advanced fluorinated dyes and pigments for optical applications and high-value coatings.
• Material Science Research: Utilized in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology Probes: Acts as a precursor for fluorescent tags and molecular probes used in biochemical assays and diagnostic research.

Basic Information

Item	Details
Product Name	4,5-Difluoro-o-phenylenediamine Dihydrochloride
CAS No.	123470-46-2
Molecular Formula	C6H6F2N2 · 2HCl
Molecular Weight	221.04 g/mol
Synonyms	4,5-Difluoro-1,2-benzenediamine dihydrochloride; 4,5-Difluoro-1,2-phenylenediamine dihydrochloride; 1,2-Diamino-4,5-difluorobenzene dihydrochloride; 4,5-Difluoro-o-phenylenediamine hydrochloride; 4,5-DFOPD · 2HCl; o-Phenylenediamine, 4,5-difluoro-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-o-phenylenediamine dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.