Description

Prulifloxacin CAS NO 123447-63-2 is a synthetic broad-spectrum fluoroquinolone antibiotic with potent activity against both Gram-positive and Gram-negative bacteria. Its primary value lies in its prodrug nature, which enhances oral bioavailability and makes it a critical active pharmaceutical ingredient (API) for systemic antibacterial therapies. This compound is essential for pharmaceutical manufacturers developing treatments for respiratory, urinary tract, and gastrointestinal infections, requiring high-purity intermediates for reliable and effective drug formulation.

Application

• Pharmaceutical API Synthesis: Serves as the key active pharmaceutical ingredient in the production of finished antibacterial drug formulations.
• Antibacterial Drug Development: Used in R&D for creating new fluoroquinolone-based medications targeting resistant bacterial strains.
• Veterinary Medicine: Employed in the development of antibacterial treatments for veterinary applications.
• Clinical Research: Utilized as a reference standard in pharmacokinetic, pharmacodynamic, and microbiological studies.
• Intermediate for Derivatives: Acts as a chemical building block for synthesizing novel quinolone derivatives with potentially improved profiles.

Basic Information

Product Name	Prulifloxacin
CAS No.	123447-63-2
Molecular Formula	C21H20FN3O6S
Molecular Weight	461.46 g/mol
Synonyms	NM441; Prulifloxacinum; UNII-4Q7P6S712C; 6-Fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl-1-piperazinyl]-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid; AF 3013; (RS)-Prulifloxacin
EINECS	Contact for details

Quality Control

Our Prulifloxacin is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and related substances tests. A Certificate of Analysis (COA) detailing all test results is provided to guarantee compliance with your specifications and regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.