Description

2,4-Difluoro-5-Nitroaniline is a versatile fluorinated aromatic amine building block, distinguished by its strategically placed fluorine and nitro substituents. This compound is critical for synthesizing advanced pharmaceutical intermediates and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and anti-infectives.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the fluorine atoms enhance lipophilicity and biological uptake.
• Dye and Pigment Manufacturing: Serves as a building block for producing specialized azo dyes and colorants with improved lightfastness and color properties.
• Material Science Research: Employed in the development of novel organic electronic materials, such as charge-transport layers and fluorinated polymers.
• Liquid Crystal & OLED Intermediates: Utilized in the synthesis of fluorinated components for display technologies, contributing to improved performance and stability.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex aniline derivatives.

Basic Information

Product Name	2,4-Difluoro-5-Nitroaniline
CAS No.	123344-02-5
Molecular Formula	C6H4F2N2O2
Molecular Weight	174.11 g/mol
Synonyms	5-Nitro-2,4-difluoroaniline; 2,4-Difluoro-5-nitrobenzenamine; 1-Amino-2,4-difluoro-5-nitrobenzene; 2,4-Difluoro-5-nitro-phenylamine; Benzenamine, 2,4-difluoro-5-nitro-; 5-Nitro-2,4-difluoroaniline; 2,4-DFNA
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Nitroaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.