Description

Dl-Histidine Monohydrochloride Monohydrate is a high-purity amino acid derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical building block and buffering agent due to its imidazole functional group. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and life science research sectors for applications ranging from cell culture media to peptide synthesis.

Application

• Pharmaceutical Intermediates: Used as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents.
• Biochemical Research: Serves as a vital component in cell culture media, enzymatic studies, and as a standard in analytical chromatography.
• Nutraceutical Formulations: Incorporated into specialized dietary supplements and clinical nutrition products requiring specific amino acid profiles.
• Peptide Synthesis: Acts as a protected amino acid building block in solid-phase and solution-phase peptide synthesis.
• Buffer Solutions: Utilized in the preparation of biological buffers, particularly in electrophoresis and protein purification processes.
• Cosmetic Ingredients: Employed in the formulation of high-end skincare products for its potential skin-conditioning properties.

Basic Information

Product Name	Dl-Histidine Monohydrochloride Monohydrate
CAS No.	123333-71-1
Molecular Formula	C6H9N3O2 • HCl • H2O
Molecular Weight	209.63 g/mol
Synonyms	DL-Histidine HCl monohydrate; (±)-Histidine hydrochloride monohydrate; Histidine, DL-, monohydrochloride, monohydrate; H-His-OH•HCl•H2O; Racemic Histidine Hydrochloride Monohydrate; 2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrochloride monohydrate
EINECS	Contact for details

Quality Control

Our Dl-Histidine Monohydrochloride Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and production use. Certificates of Analysis (COA) documenting purity, heavy metals, residual solvents, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.5%
Optical Rotation	-0.10° to +0.10°
Loss on Drying	≤ 8.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Chloride Content	16.5 - 17.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.