Description

2,3-Difluoro-4-Nitro-Phenol is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both nitro and phenolic groups on a difluorinated benzene ring, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and anti-infective applications.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its fluorinated aromatic core.
• Polymer & Resin Modifier: Acts as a monomer or additive to introduce fluorine atoms into polymer chains, improving chemical resistance and thermal stability.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where fluorine substitution alters light absorption and color fastness.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures.

Basic Information

Product Name	2,3-Difluoro-4-Nitro-Phenol
CAS No.	123173-60-4
Molecular Formula	C6H3F2NO3
Molecular Weight	175.09 g/mol
Synonyms	2,3-Difluoro-4-nitrophenol; 4-Nitro-2,3-difluorophenol; Phenol, 2,3-difluoro-4-nitro-; 2,3-Difluoro-4-nitro-1-hydroxybenzene; 2,3-DFNP
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Nitro-Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.