Description

Neuropeptide Y (2-36) (Human, Rat) is a specific, biologically active fragment of the full-length Neuropeptide Y (NPY) hormone. This high-purity peptide is critical for advanced research into the NPY system, which plays a fundamental role in regulating energy balance, anxiety, and cardiovascular function. It is an essential biochemical tool for pharmaceutical R&D, academic research, and diagnostic development focused on metabolic and neurological disorders. CAS NO 123139-39-9.

Application

• Neuroscience Research: Used as a selective ligand to study NPY Y1, Y2, and Y5 receptor subtypes and their signaling pathways in the central and peripheral nervous systems.
• Metabolic Disorder Studies: Employed in preclinical research to investigate the role of NPY in appetite regulation, obesity, and diabetes.
• Cardiovascular Research: Applied in studies exploring NPY's effects on blood pressure, heart rate, and vascular tone.
• Biochemical Assay Development: Serves as a reference standard and key component in the development of competitive binding assays (e.g., RIA, ELISA) and functional cellular assays.
• Drug Discovery & Screening: Used as a tool compound in high-throughput screening (HTS) campaigns to identify novel NPY receptor agonists or antagonists.
• Academic & Institutional Research: A fundamental reagent for basic science investigating stress responses, anxiety, depression, and related behavioral models.

Basic Information

Product Name	Neuropeptide Y (2-36) (Human, Rat)
CAS No.	123139-39-9
Molecular Formula	C185H285N55O57S
Molecular Weight	4252.6 g/mol
Synonyms	NPY (2-36); Neuropeptide Y Fragment 2-36; h/rNPY (2-36); Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; Human, Rat Neuropeptide Y (2-36) amide; [Tyr2, Tyr36]-Neuropeptide Y (2-36) amide
EINECS	Contact for details

Quality Control

Our Neuropeptide Y (2-36) (Human, Rat) is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry for identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data on purity, peptide content, water content (by KF), and endotoxin levels where applicable, supporting research requiring reproducible and reliable results.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use vials after reconstitution to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.