Description

L-3-Chlorophenylalanine is a halogenated derivative of the essential amino acid phenylalanine, featuring a chlorine atom at the meta position of the phenyl ring. This specific structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. The compound's defined stereochemistry is critical for developing active compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Research: Building block for developing new herbicides, pesticides, and plant growth regulators with enhanced specificity.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a chlorinated aromatic moiety into peptide sequences for structure-activity relationship (SAR) studies.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, helping to probe enzyme mechanisms and active sites.
• Material Science: Intermediate for synthesizing specialty polymers and liquid crystals where the chlorophenyl group influences material properties.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control.

Basic Information

Product Name	L-3-Chlorophenylalanine
CAS No.	123053-22-5
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	(S)-2-Amino-3-(3-chlorophenyl)propanoic acid; L-3-Chloro-phenylalanine; L-β-(3-Chlorophenyl)alanine; (S)-3-(3-Chlorophenyl)alanine; L-m-Chlorophenylalanine; 3-Chloro-L-phenylalanine; H-3-Cl-Phe-OH
EINECS	Contact for details

Quality Control

Our L-3-Chlorophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and production use. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.