Description

Ethyl 8-Methyl-4-Oxo-6-Phenyl-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, especially for central nervous system (CNS) and anti-infective applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex nitrogen and sulfur-containing heterocyclic core.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of structure-activity relationships (SAR) in drug discovery programs.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research on fused pyrimidine-thiazine chemistry.
• Process Development & Scale-Up: Used by process chemists to develop and optimize scalable synthetic routes for target molecules in kilo-lab and pilot plant settings.

Basic Information

Product Name	Ethyl 8-Methyl-4-Oxo-6-Phenyl-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate
CAS No.	123044-08-6
Molecular Formula	C₁₇H₁₈N₂O₃S
Molecular Weight	330.40 g/mol
Synonyms	Ethyl 8-methyl-4-oxo-6-phenyl-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; 7-Carbethoxy-8-methyl-6-phenyl-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazin-4-one; 6-Phenyl-8-methyl-4-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid ethyl ester; CAS 123044-08-6; Pyrimido[2,1-b][1,3]thiazine-7-carboxylate derivative
EINECS	Contact for details

Quality Control

Our Ethyl 8-Methyl-4-Oxo-6-Phenyl-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.