Description

Somatotropin Releasing Hormone (1-29) Amide, 27-Leu- is a bioactive synthetic peptide analog of growth hormone-releasing hormone (GHRH). This compound is critical for research and development in endocrinology and metabolic studies due to its specific activity in stimulating the release of growth hormone. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents for growth disorders and metabolic diseases.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of growth hormone secretagogues and related therapeutics.
• Endocrinology Studies: Used in in vitro and in vivo research to investigate the pituitary gland function, growth hormone regulation, and associated signaling pathways.
• Metabolic Disorder Research: Applied in preclinical studies targeting conditions related to growth hormone deficiency, aging, and metabolic syndrome.
• Biochemical Assay Development: Serves as a critical component in the development and validation of bioassays and immunoassays for GHRH activity.
• Peptide Chemistry & Synthesis: Used as a building block or intermediate for the synthesis of more complex peptide analogs with modified biological activity.

Basic Information

Product Name	Somatotropin Releasing Hormone (1-29) Amide, 27-Leu-
CAS No.	123041-18-9
Molecular Formula	C149H246N44O42S
Molecular Weight	3359.9 g/mol
Synonyms	GHRH (1-29) amide, 27-Leu-; Somatoliberin (1-29) amide, 27-Leu-; Growth Hormone-Releasing Hormone (1-29)-NH2, [Leu27]hGHRH(1-29)NH2; [Leu27]hGRF(1-29)NH2; Tesamorelin precursor; GRF (1-29) amide, human, Leu27-; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2
EINECS	Contact for details

Quality Control

Our Somatotropin Releasing Hormone (1-29) Amide, 27-Leu- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.