Description

Pyrimidine, 2,5-Difluoro-4-Methoxy- (9Ci) is a high-value, multi-functional fluorinated pyrimidine building block. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including potential antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atoms improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Fluorine Chemistry & Catalysis Research: Employed in academic and industrial research to study novel fluorination reactions and develop new catalytic processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke fluorinated compounds for clients.

Basic Information

Product Name	Pyrimidine, 2,5-Difluoro-4-Methoxy- (9Ci)
CAS No.	123038-80-2
Molecular Formula	C5H4F2N2O
Molecular Weight	146.10 g/mol
Synonyms	2,5-Difluoro-4-methoxypyrimidine; 4-Methoxy-2,5-difluoropyrimidine; 2,5-Difluoro-4-methoxy-1,3-diazine; 2,5-Difluoro-4-methoxypyrimidine (9CI); Difluoromethoxypyrimidine; Fluorinated pyrimidine ether; Pyrimidine, 4-methoxy-2,5-difluoro-
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2,5-Difluoro-4-Methoxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.