Description

4-Pyrimidinamine, 2,5-Difluoro- (9Ci) is a high-purity fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced biological activity and stability.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and labeled compounds used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and fine chemical production on a commercial scale.

Basic Information

Product Name	4-Pyrimidinamine, 2,5-Difluoro- (9Ci)
CAS No.	123038-79-9
Molecular Formula	C4H3F2N3
Molecular Weight	131.09 g/mol
Synonyms	2,5-Difluoropyrimidin-4-amine; 2,5-Difluoro-4-pyrimidinamine; 4-Amino-2,5-difluoropyrimidine; 2,5-Difluoro-4-aminopyrimidine; 2,5-Difluoropyrimidine-4-amine; 4-Pyrimidinamine, 2,5-difluoro-; 2,5-Difluoro-4-pyrimidinylamine
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinamine, 2,5-Difluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.