Description

3-Fluoro-4-Iodophenol is a halogenated phenol derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, where the fluorine and iodine atoms contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions, such as Suzuki and Sonogashira couplings.
• Material Science Research: Employed in the creation of organic electronic materials, including monomers for conductive polymers and components for organic light-emitting diodes (OLEDs).
• Fluorinated Compound Libraries: An essential building block for medicinal chemistry and combinatorial chemistry to create diverse libraries of fluorinated compounds for high-throughput screening.
• Diagnostic Agent Precursor: Potential use in the synthesis of radiolabeled compounds or contrast agents for medical imaging applications.

Basic Information

Item	Details
Product Name	3-Fluoro-4-Iodophenol
CAS No.	122927-84-8
Molecular Formula	C6H4FIO
Molecular Weight	237.99 g/mol
Synonyms	4-Iodo-3-fluorophenol; 3-Fluoro-4-hydroxyiodobenzene; 1-Fluoro-2-hydroxy-5-iodobenzene; Phenol, 3-fluoro-4-iodo-; 3-Fluoro-p-iodophenol; FIP; 3F4IP
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Iodophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.