Description

N4-Benzo[1,3]Dioxol-5-Ylmethyl-6-Chloro-Pyrimidine-2,4-Diamine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique molecular scaffold enables the creation of targeted bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrimidine-diamine structure.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in custom synthesis and contract manufacturing projects.
• Biochemical Tool Compound: Potential use in life science research as a probe or inhibitor to study specific enzymatic pathways.
• Material Science Precursor: Can be utilized in the synthesis of specialized organic ligands or functional materials.

Basic Information

Product Name	N4-Benzo[1,3]Dioxol-5-Ylmethyl-6-Chloro-Pyrimidine-2,4-Diamine
CAS No.	122862-27-5
Molecular Formula	C12H11ClN4O2
Molecular Weight	278.70 g/mol
Synonyms	6-Chloro-N4-[(1,3-benzodioxol-5-yl)methyl]pyrimidine-2,4-diamine; 2,4-Diamino-6-chloro-N-(1,3-benzodioxol-5-ylmethyl)pyrimidine; 6-Chloro-N4-(piperonyl)pyrimidine-2,4-diamine; N4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-chloropyrimidine-2,4-diamine; 122862-27-5; 6-Chloro-N-(1,3-benzodioxol-5-ylmethyl)pyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our N4-Benzo[1,3]Dioxol-5-Ylmethyl-6-Chloro-Pyrimidine-2,4-Diamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.