Description

2-Fluoro-D-Phenylalanine is a fluorinated, non-natural amino acid derivative of significant interest in advanced pharmaceutical and biochemical research. Its core value lies in its role as a key chiral building block for the synthesis of novel peptides and bioactive compounds, where the fluorine atom can modulate metabolic stability, lipophilicity, and receptor binding affinity. This high-purity enantiomer is essential for researchers and manufacturers in the pharmaceutical industry, particularly in the development of peptide-based therapeutics, enzyme inhibitors, and as a standard in analytical method development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel peptide drugs and enzyme inhibitors.
• Biochemical Research: Used as a non-natural amino acid probe to study protein structure, function, and enzyme-substrate interactions.
• Peptide Synthesis: Incorporated into custom peptides to enhance metabolic stability and alter biological activity through fluorine substitution.
• Standards & Reference Materials: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Agrochemical Research: Potential application as a building block for the synthesis of advanced, bioactive compounds.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in sophisticated organic synthesis routes.

Basic Information

Product Name	2-Fluoro-D-Phenylalanine
CAS No.	122839-51-4
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	(R)-2-Amino-3-(2-fluorophenyl)propanoic acid; D-2-Fluorophenylalanine; (R)-2-Fluorophenylalanine; D-α-Amino-2-fluorobenzenepropanoic acid; F-D-Phe-OH; 2-F-D-Phe; (2R)-2-Amino-3-(2-fluorophenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-D-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.