Description

γ-Cycloglutamyl Phosphate is a specialized cyclic glutamyl phosphate derivative with significant potential in advanced biochemical research and synthesis. This compound serves as a crucial phosphorylated intermediate and building block for the development of novel peptides, enzyme inhibitors, and nucleotide analogs. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, proteomics, and the study of phosphate transfer mechanisms.

Application

• Medicinal Chemistry & Drug Discovery: As a key intermediate for synthesizing novel peptide-based therapeutics and enzyme inhibitors targeting phosphate-dependent pathways.
• Biochemical Research: Utilized as a substrate or analog in enzymatic studies, particularly those involving kinases, phosphatases, and ATP-dependent processes.
• Proteomics & Peptide Synthesis: Serves as a phosphorylated building block for the solid-phase or solution-phase synthesis of modified peptides for structural and functional studies.
• Nucleotide Analog Development: Acts as a precursor in the design and synthesis of modified nucleotides or nucleotide-like compounds with potential antiviral or anticancer activity.
• Chemical Biology Probes: Used to create activity-based probes for labeling and studying phosphate-binding proteins and enzymes in complex biological systems.

Basic Information

Product Name	γ-Cycloglutamyl Phosphate
CAS No.	122651-69-8
Molecular Formula	C5H8NO6P
Molecular Weight	209.10 g/mol
Synonyms	γ-Cycloglutamyl Phosphate; (3S)-3-Amino-1-hydroxy-2,5-dioxo-1λ5-phospholane-1-oxide; 1-Hydroxy-3-azabicyclo[3.1.0]hexane-2,4-dione 1-oxide; Cycloglutamyl Phosphate; Glutamyl Phosphate Cyclic Derivative; L-γ-Cycloglutamyl Phosphoric Acid; Phosphoric Acid Mono[(3S)-3-amino-2,5-dioxo-1-phospholanyl] Ester
EINECS	Contact for details

Quality Control

Our γ-Cycloglutamyl Phosphate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Quality is verified through a suite of analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed in a desiccated environment to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.