Description

L-Phe(4-Coch3) is a chemically modified derivative of the essential amino acid L-Phenylalanine, specifically acetylated at the para position of the phenyl ring. This modification imparts unique steric and electronic properties, making it a valuable non-natural amino acid building block for advanced research and synthesis. It is primarily utilized by pharmaceutical researchers and peptide chemists in the development of novel bioactive compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified phenylalanine residues, altering peptide stability, bioavailability, and receptor binding affinity.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent probes, affinity labels, or linkers in bioconjugation chemistry due to its reactive acetyl group.
• Chemical Biology Research: Employed in studying enzyme mechanisms, protein-protein interactions, and metabolic pathways by acting as a substrate analog or inhibitor.
• Material Science: Potential use as a monomer or functional additive in the synthesis of specialized polymers with enhanced properties.

Basic Information

Product Name	L-Phe(4-Coch3)
CAS No.	122555-04-8
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	N-Acetyl-L-tyrosine; L-4-Acetoxyphenylalanine; (2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoic acid acetate; 4-Acetoxy-L-phenylalanine; Ac-L-Tyr-OH; N-Acetyl-L-tyrosine acetate ester; Modified L-Phenylalanine derivative; Para-acetylated L-Phe
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our L-Phe(4-Coch3) is typically produced to research-grade standards, with purity often exceeding 97% (HPLC). Identity and purity are confirmed by analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing specific results for each batch is provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.