Description

4-(Aminomethyl)-3-(Trifluoromethyl)Aniline is a versatile aromatic amine building block featuring both an aminomethyl and a trifluoromethyl substituent on the aniline ring. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and high-performance agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Incorporated into polymer backbones or as a cross-linking agent to impart specific thermal and chemical resistance properties.
• Dye and Pigment Intermediate: Utilized in the synthesis of advanced colorants and functional dyes with enhanced lightfastness.
• Research & Development: A valuable reagent for medicinal chemistry and discovery chemistry programs in academic and industrial settings.

Basic Information

Product Name	4-(Aminomethyl)-3-(Trifluoromethyl)Aniline
CAS No.	122509-22-2
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	3-(Trifluoromethyl)-4-(aminomethyl)aniline; 4-(Aminomethyl)-3-(trifluoromethyl)benzenamine; 3-Trifluoromethyl-4-aminomethylaniline; Benzenamine, 4-(aminomethyl)-3-(trifluoromethyl)-; 4-(Aminomethyl)-alpha,alpha,α-trifluoro-m-toluidine; 4-Aminomethyl-3-trifluoromethylphenylamine
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-3-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.