Description

Angiotensin I/II (3-7) is a bioactive peptide fragment derived from the renin-angiotensin system. This compound is a critical research tool for studying cardiovascular physiology, neurobiology, and metabolic regulation. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers focused on hypertension, heart failure, and related metabolic disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of the renin-angiotensin system (RAS), blood pressure regulation, and cardiac function.
• Pharmaceutical Development: Serves as a key intermediate or pharmacophore in the discovery and screening of novel antihypertensive and cardioprotective drugs.
• Diagnostic Assays: Employed as a calibrator or antigen in the development of immunoassays (ELISA, RIA) for measuring angiotensin peptide levels in biological samples.
• Neurobiological Studies: Investigated for its role in the central nervous system, including effects on thirst, vasopressin release, and sympathetic outflow.
• Cell Signaling & Receptor Studies: Applied in in vitro and in vivo models to elucidate angiotensin receptor (AT1, AT2) signaling pathways and interactions.
• Metabolic Research: Explored for its influence on insulin sensitivity, adipose tissue function, and other metabolic parameters linked to cardiovascular disease.

Basic Information

Product Name	Angiotensin I/II (3-7)
CAS No.	122483-84-5
Molecular Formula	C27H44N8O7
Molecular Weight	592.69 g/mol
Synonyms	Angiotensin (3-7); Angiotensin II (3-7); Angiotensin I (3-7); Arg-Val-Tyr-Ile-His-Pro-Phe; RVYIHPF; H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; [Des-Asp1, Arg2]-Angiotensin I
EINECS	Contact for details

Quality Control

Our Angiotensin I/II (3-7) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.