Description

H-Tyr-Pro-Pro-Trp-Oh is a synthetic tetrapeptide with the sequence Tyr-Pro-Pro-Trp. This compound is of significant interest in biochemical and pharmaceutical research due to its specific amino acid sequence, which can influence biological activity and stability. It serves as a crucial intermediate or reference standard for researchers in peptide synthesis, drug discovery, and the development of bioactive molecules. Target industries include pharmaceutical R&D, biotechnology, and academic research institutions focused on peptide-based therapeutics and analytical method development.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a reference standard or substrate in enzymatic studies, receptor-ligand binding assays, and structure-activity relationship (SAR) investigations.
• Peptide Library Synthesis: A valuable building block for constructing combinatorial peptide libraries used in high-throughput screening for biological activity.
• Analytical Standard: Employed as a certified reference material (CRM) for method validation, quality control, and calibration in HPLC, LC-MS, and other analytical techniques.
• Cosmeceutical Development: Investigated for potential applications in advanced skincare formulations targeting specific biological pathways.
• Academic Studies: Utilized in university and institutional labs for teaching and research in peptide chemistry, medicinal chemistry, and molecular biology.

Basic Information

Product Name	H-Tyr-Pro-Pro-Trp-Oh
CAS No.	122409-34-1
Molecular Formula	C33H39N5O6
Molecular Weight	601.70 g/mol
Synonyms	Tyr-Pro-Pro-Trp; H-Tyr-Pro-Pro-Trp-OH; L-Tyrosyl-L-prolyl-L-prolyl-L-tryptophan; Tetrapeptide TYR-PRO-PRO-TRP; YPPW; Tryptophan, L-tyrosyl-L-prolyl-L-prolyl-; 122409-34-1; L-Tyrosyl-L-prolyl-L-prolyl-L-tryptophan
EINECS	Contact for details

Quality Control

Our H-Tyr-Pro-Pro-Trp-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity checks, to ensure it meets high-grade specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (on dried basis)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.