Description

H-Tyr-Pro-Trp-Oh is a synthetic tripeptide derivative, a key building block in advanced pharmaceutical and biochemical research. Its defined structure makes it an essential intermediate for the development of novel peptide-based therapeutics and diagnostic agents. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of more complex peptide drugs and hormone analogs.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, receptor binding assays, and metabolic pathway investigations.
• Proteomics & Peptide Library Synthesis: Serves as a defined sequence unit for constructing custom peptide libraries for high-throughput screening.
• Academic Research: Employed in universities and research institutes for studying peptide structure-activity relationships (SAR) and folding properties.
• Diagnostic Reagent Development: Potential use in the development of labeled peptides for immunoassays and imaging probes.

Basic Information

Product Name	H-Tyr-Pro-Trp-Oh
CAS No.	122409-33-0
Molecular Formula	C25H28N4O5
Molecular Weight	464.52 g/mol
Synonyms	L-Tyrosyl-L-prolyl-L-tryptophan; Tyr-Pro-Trp; H-Tyr-Pro-Trp-OH; Triptorelin related peptide A; L-Tyrosyl-L-prolyl-L-tryptophan; YPW; Tripeptide Y-P-W; (S)-2-((S)-1-((S)-2-Amino-3-(1H-indol-3-yl)propanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our H-Tyr-Pro-Trp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation by mass spectrometry (MS) and infrared spectroscopy (IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.