Description

Amylin, Human CAS NO 122384-88-7 is a 37-amino acid peptide hormone co-secreted with insulin from the pancreatic β-cells. This compound is critical for research into metabolic regulation, particularly glucose homeostasis and satiety signaling. It is an essential biochemical tool for pharmaceutical R&D, academic research, and diagnostic development focused on diabetes, obesity, and related metabolic disorders.

Application

• Pharmaceutical Research & Development: Primary reference standard for the development of amylin analogs (e.g., pramlintide) and metabolic disease therapeutics.
• Biochemical & Metabolic Studies: Used in in vitro and in vivo research to investigate its role in gastric emptying, glucagon secretion, and appetite regulation.
• Diagnostic Assay Development: Serves as a critical calibrant and antigen in the production of immunoassays (ELISA, RIA) for measuring amylin levels in biological samples.
• Cell Signaling & Receptor Binding Studies: Essential ligand for studying amylin receptor (AMY) activation and downstream signaling pathways.
• Quality Control & Standardization: Used as a high-purity standard in QC laboratories for verifying the identity and potency of related pharmaceutical products.

Basic Information

Product Name	Amylin, Human
CAS No.	122384-88-7
Molecular Formula	C165H267N51O53S2
Molecular Weight	3903.4 g/mol
Synonyms	Human Islet Amyloid Polypeptide (hIAPP); IAPP (37AA); Diabetes-Associated Peptide; Amylin (1-37), human; DAP; hAmylin; INS2; Islet Amyloid Polypeptide Precursor
EINECS	Contact for details

Quality Control

Our Amylin, Human is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) providing batch-specific data is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.