Description

2-Bromo-4,5,6-Trifluoroaniline is a high-value, multi-fluorinated aromatic amine building block, distinguished by its unique halogen and fluorine substitution pattern. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures, enabling the fine-tuning of material characteristics and biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design of fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex heterocyclic and polycyclic compounds.

Basic Information

Product Name	2-Bromo-4,5,6-Trifluoroaniline
CAS No.	122375-82-0
Molecular Formula	C6H2BrF3N
Molecular Weight	227.99 g/mol
Synonyms	2-Bromo-4,5,6-trifluorobenzenamine; 4,5,6-Trifluoro-2-bromoaniline; Benzenamine, 2-bromo-4,5,6-trifluoro-; 2-Bromo-4,5,6-trifluoro-phenylamine; 2-Br-4,5,6-F3-C6HNH2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,5,6-Trifluoroaniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA), including results for purity (HPLC), identity (IR, NMR), and specific impurity profiles, is supplied with each shipment to guarantee reproducible performance and supply chain traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.