Description

Neuropeptide Y (13-36), Human, Rat is a specific C-terminal fragment of the full-length Neuropeptide Y (NPY) hormone. This peptide sequence is a critical research tool for studying the structure-activity relationships and receptor binding profiles of NPY, particularly its interaction with Y2 receptor subtypes. It is essential for neuroscientists, pharmacologists, and biochemists engaged in metabolic, cardiovascular, and appetite regulation research. The compound is supplied with high purity to ensure reliable and reproducible experimental results.

Application

• Neuroscience Research: Investigation of NPY's role in feeding behavior, anxiety, stress response, and circadian rhythms.
• Receptor Binding Studies: Used as a selective ligand to characterize and map Y2 receptor distribution and affinity.
• Metabolic Disorder Research: Studying the peptide's influence on energy homeostasis, obesity, and diabetes pathways.
• Cardiovascular Research: Exploring NPY's effects on blood pressure regulation and vascular tone.
• Biochemical Assay Development: Serving as a standard or control in ELISA, RIA, and other immunoassay platforms.
• Structure-Activity Relationship (SAR) Analysis: Key fragment for understanding the bioactive core of the full NPY molecule.
• Academic & Pharmaceutical R&D: Fundamental tool for basic research and early-stage drug discovery targeting NPY receptors.

Basic Information

Product Name	Neuropeptide Y (13-36), Human, Rat
CAS No.	122341-40-6
Molecular Formula	C119H187N41O34
Molecular Weight	2705.0 g/mol (approximate)
Synonyms	NPY (13-36); Neuropeptide Y Fragment 13-36; Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 (human/rat sequence); NPY (13-36), human; NPY (13-36), rat; Y2 Receptor Ligand (13-36); NPY C-terminal Fragment
EINECS	Contact for details

Quality Control

Every batch of Neuropeptide Y (13-36), Human, Rat is manufactured and analyzed under strict quality protocols. We guarantee high purity levels, typically >95% as determined by analytical HPLC, and provide full characterization data including mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and peptide content are available upon request for complete traceability and assurance.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Complies with theoretical composition
Solubility	Soluble in water, dilute acetic acid, or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.