Description

Eglin C (60-63) CAS NO 122299-14-3 is a synthetic peptide fragment derived from the natural serine protease inhibitor Eglin c. This compound is a high-purity biochemical reagent valued for its potent and specific inhibitory activity against key proteolytic enzymes. It serves as a critical research tool for scientists in biochemistry and pharmacology, enabling the study of protease mechanisms and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specific inhibitor in enzymatic assays to study the kinetics and function of serine proteases like chymotrypsin, subtilisin, and elastase.
• Pharmaceutical Development: Acts as a lead compound or reference standard in drug discovery programs targeting inflammatory diseases and conditions involving excessive proteolysis.
• Protease Mechanism Studies: Essential for elucidating enzyme-inhibitor interactions, binding affinities, and the structural basis of inhibition through X-ray crystallography and NMR spectroscopy.
• Diagnostic Reagent Component: May be incorporated into in-vitro diagnostic kits to control or modulate protease activity in clinical sample analysis.
• Cell Culture & Biotechnology: Employed in cell-based assays to inhibit specific proteases, helping to understand their role in cellular signaling pathways and protein processing.

Basic Information

Product Name	Eglin C (60-63)
CAS No.	122299-14-3
Molecular Formula	C23H38N8O7
Molecular Weight	538.6 g/mol
Synonyms	Eglin c (60-63); Eglin C fragment 60-63; H-Arg-Cys-Met-Arg-OH; L-Arginyl-L-cysteinyl-L-methionyl-L-arginine; RCMR peptide; Chymotrypsin inhibitor Eglin c (60-63); Protease inhibitor peptide (60-63).
EINECS	Contact for details

Quality Control

Our Eglin C (60-63) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry (MS) for identity confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.