Description

3,5-Difluoro-4-Nitroaniline is a high-purity aromatic amine derivative characterized by its nitro and fluorine substituents, which confer unique reactivity and electronic properties. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in the synthesis of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a building block for producing specialized azo dyes and pigments with specific color fastness and spectral properties.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and nitro-group transformations.

Basic Information

Item	Detail
Product Name	3,5-Difluoro-4-Nitroaniline
CAS No.	122129-79-7
Molecular Formula	C6H4F2N2O2
Molecular Weight	174.11 g/mol
Synonyms	4-Nitro-3,5-difluoroaniline; 3,5-Difluoro-4-nitrobenzenamine; 2,6-Difluoro-4-nitroaniline; 1-Amino-3,5-difluoro-4-nitrobenzene; 4-Amino-2,6-difluoronitrobenzene; DFNA; 3,5-DF-4-NA
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Nitroaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. We provide a Certificate of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures reliable batch-to-batch consistency and traceability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.