Description

n-Acetyl-Gastrin Releasing Peptide Ethyl Ester is a chemically modified derivative of the neuropeptide Gastrin-Releasing Peptide (GRP), designed for enhanced stability and research utility. This compound is a critical tool for investigating the GRP signaling pathway, which plays a significant role in cellular communication, growth, and various physiological processes. It is primarily utilized by research scientists and pharmaceutical developers in the fields of neuroscience, oncology, and gastrointestinal research for in vitro and in vivo studies.

Application

• Biomedical Research: Used as a stable analog to study the biological functions and receptor binding mechanisms of Gastrin-Releasing Peptide (GRP).
• Neuroscience Studies: Investigation of GRP's role in the central nervous system, including its effects on behavior, thermoregulation, and synaptic transmission.
• Oncology Research: Exploration of the GRP/GRP receptor pathway in cancer cell proliferation, particularly in lung, prostate, and gastrointestinal cancers.
• Pharmacological Assay Development: Serves as a reference standard or active agent in developing high-throughput screening assays for drug discovery.
• Biochemical Tool: Used in structure-activity relationship (SAR) studies to design and evaluate new peptide-based therapeutics.
• Academic & Institutional Research: Fundamental research in university and institutional labs focusing on peptide chemistry and neuroendocrinology.

Basic Information

Product Name	n-Acetyl-Gastrin Releasing Peptide Ethyl Ester
CAS No.	122000-99-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Acetyl-GRP Ethyl Ester; N-Acetyl-GRP Ethyl Ester; GRP (14-27), N-acetyl-, ethyl ester; Acetylated Gastrin Releasing Peptide Ethyl Ester; n-Acetyl GRP EE; Bombesin-like peptide derivative; Research Peptide 122000-99-1
EINECS	Contact for details

Quality Control

Our n-Acetyl-Gastrin Releasing Peptide Ethyl Ester is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. All materials are characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, acetic acid; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.