Description

Acetyl-Arg-Phe-Phe-Sar-Leu-Met[O2] is a synthetic peptide derivative, specifically a modified hexapeptide containing the oxidized methionine (Met[O2]) residue. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its role as a potential protease substrate or inhibitor mimic. It serves as a critical intermediate or reference standard for researchers in proteomics, enzymology, and drug discovery. Target users include biotechnology firms, academic research institutions, and pharmaceutical companies engaged in peptide-based therapeutic and diagnostic development.

Application

• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly for investigating protease activity and kinetics.
• Pharmaceutical R&D: Serves as a key intermediate or building block in the synthesis of novel peptide-based drug candidates and molecular probes.
• Proteomics & Biomarker Discovery: Employed as a reference standard in mass spectrometry and HPLC analysis for method development and validation in complex biological samples.
• Enzyme Mechanism Studies: Utilized to study the effects of methionine oxidation on peptide structure, function, and interaction with biological targets.
• Quality Control Standard: Acts as a high-purity certified reference material (CRM) for calibrating analytical instruments and ensuring accuracy in peptide quantification.

Basic Information

Product Name	Acetyl-Arg-Phe-Phe-Sar-Leu-Met[O2]
CAS No.	121951-71-1
Molecular Formula	C46H69N13O11S
Molecular Weight	1004.2 g/mol
Synonyms	Ac-Arg-Phe-Phe-Sar-Leu-Met(O2); Ac-RFFSarLM(O2); N-Acetyl-L-arginyl-L-phenylalanyl-L-phenylalanyl-sarcosyl-L-leucyl-L-methionine sulfone; Acetyl-Arg-Phe-Phe-Sar-Leu-Methionine Sulfone; Hexapeptide Ac-RFFSarLM(O2); [Ac-Arg-Phe-Phe-Sar-Leu-Met(O2)]; Ac-RFFSar-Leu-Met(O2); Acetylated RFFSarLM(O2) Peptide
EINECS	Contact for details

Quality Control

Our Acetyl-Arg-Phe-Phe-Sar-Leu-Met[O2] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Impurity	≤ 2.0%
Amino Acid Composition	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.