Description

Cholecystokinin Octapeptide (1-5) (Desulfated) is a bioactive peptide fragment derived from the gastrointestinal hormone cholecystokinin. This compound is a valuable research tool for studying receptor binding, signal transduction, and the physiological roles of CCK in the central nervous system and digestive tract. It is primarily utilized by pharmaceutical researchers, biochemical suppliers, and academic institutions engaged in neuroscience, endocrinology, and peptide chemistry studies. The desulfated form offers specific insights into structure-activity relationships.

Application

• Neuroscience Research: Investigation of CCK receptor subtypes (CCKA and CCKB) in the brain, studying anxiety, satiety, and pain modulation.
• Biochemical Assay Development: Used as a reference standard or competitive ligand in receptor binding assays and radioimmunoassays (RIA).
• Pharmacological Studies: Exploring the role of CCK in pancreatic secretion, gallbladder contraction, and gut motility.
• Peptide Chemistry & Drug Discovery: Serving as a key intermediate or analog in the design of novel neuropeptide-based therapeutics.
• Academic & Institutional Research: Fundamental research on peptide hormones, their fragments, and post-translational modifications like sulfation.

Basic Information

Product Name	Cholecystokinin Octapeptide (1-5) (Desulfated)
CAS No.	121880-96-4
Molecular Formula	C38H55N9O9S
Molecular Weight	813.97 g/mol
Synonyms	CCK-8 (1-5), Desulfated; CCK Octapeptide Fragment (1-5), Desulfated; H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (1-5), Desulfated; Cholecystokinin (26-33) (1-5) Fragment, Desulfated; Sincalide (1-5) Fragment, Desulfated; CCK-8 (desulfated) (1-5); Asp-Tyr-Met-Gly-Trp-Met (Desulfated)
EINECS	Contact for details

Quality Control

Our Cholecystokinin Octapeptide (1-5) (Desulfated) is produced and tested under strict quality management systems. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, related substances, and residual solvents, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.