Description

Hirugen CAS NO 121822-23-9 is a synthetic peptide inhibitor specifically designed to target the thrombin anion-binding exosite I. This compound is a critical research tool for studying the mechanisms of blood coagulation and thrombosis. It is primarily utilized by pharmaceutical researchers and academic institutions in the fields of cardiovascular biology and hematology. Its high specificity makes it invaluable for developing novel antithrombotic therapies and diagnostic assays.

Application

• Biochemical Research: As a selective inhibitor to study thrombin's structure, function, and interaction with substrates like fibrinogen and PARs.
• Drug Discovery: A key reference compound and screening tool in the development of new anticoagulant and antithrombotic agents.
• Diagnostic Assay Development: Used to validate and calibrate in vitro assays measuring thrombin activity and inhibition.
• Academic Studies: Fundamental research into hemostasis, thrombosis, and related vascular diseases.

Basic Information

Product Name	Hirugen
CAS No.	121822-23-9
Molecular Formula	C96H138N24O31S2
Molecular Weight	2092.4 g/mol
Synonyms	Hirugen (Thrombin Inhibitor); D-Phe-Pro-Arg-Pro-(Gly)4; Hirugen peptide; Thrombin exosite I inhibitor; (D-Phe)-Pro-Arg-Pro-(Gly)4; H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH (related sequence); Synthetic hirudin fragment; Anticoagulant peptide.
EINECS	Contact for details

Quality Control

Every batch of Hirugen is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) that include data for purity, identity, and peptide content. Our quality standards are designed to meet the rigorous demands of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.