Description

D-Cyclopropylalanine is a non-proteinogenic amino acid derivative featuring a cyclopropyl side chain, which imparts unique conformational and steric properties. This chiral building block is of significant value in medicinal chemistry for the design and synthesis of novel bioactive compounds. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis professionals to create peptidomimetics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, enzyme modulators, and other targeted therapeutics.
• Peptidomimetics Research: Used to incorporate conformational constraints into peptide backbones, enhancing metabolic stability and receptor selectivity.
• Agrochemical Development: Serves as a building block for novel herbicides and pesticides with specific modes of action.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands for asymmetric synthesis and metal catalysis.
• Biochemical Tool Development: Useful for probing enzyme active sites and studying structure-activity relationships (SAR).
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in both university laboratories and corporate research centers.

Basic Information

Product Name	D-Cyclopropylalanine
CAS No.	121786-39-8
Molecular Formula	C₆H₁₁NO₂
Molecular Weight	129.16 g/mol
Synonyms	(R)-2-Amino-2-cyclopropylacetic acid; D-2-Cyclopropylglycine; (R)-2-Cyclopropylglycine; D-α-Cyclopropylglycine; (R)-Amino(cyclopropyl)acetic acid; D-Cyclopropylglycine; (2R)-2-Amino-2-cyclopropylethanoic acid; UNII-9J3H2B6T8F
EINECS	Contact for details

Quality Control

Our D-Cyclopropylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.