Description

21S-Argatroban is a potent and selective direct thrombin inhibitor, a critical active pharmaceutical ingredient (API) in the synthesis of anticoagulant medications. Its high specificity makes it a valuable compound for developing therapies that require precise control of blood coagulation. This product is essential for pharmaceutical manufacturers and research institutions focused on cardiovascular disease treatment, particularly for patients with heparin-induced thrombocytopenia (HIT).

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of injectable anticoagulant drugs.
• Cardiovascular Research: Used in biochemical and pharmacological studies to investigate thrombin inhibition mechanisms.
• Anticoagulant Formulation: Key component in the development of novel parenteral formulations for acute coronary syndromes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical labs.
• Biochemical Reagent: Utilized in vitro for studying blood coagulation pathways and enzyme kinetics.

Basic Information

Product Name	21S-Argatroban
CAS No.	121785-72-6
Molecular Formula	C23H36N6O5S
Molecular Weight	508.64 g/mol
Synonyms	Argatroban; (2R,4R)-4-Methyl-1-[N2-((RS)-3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl]-2-piperidinecarboxylic acid; MD-805; Novastan; Slonnon; Argipidine; (2R,4R)-4-Methyl-1-[N2-(3-methyl-1,2,3,4-tetrahydro-8-quinolinylsulfonyl)-L-arginyl]-2-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 21S-Argatroban is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting compliance with relevant standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.