Description

N',N''-Diethylnorspermine Tetrahydrochloride is a high-purity, polyamine-based research chemical of significant interest in biochemical and pharmacological studies. This compound serves as a potent and selective inhibitor of polyamine biosynthesis, making it a critical tool for investigating cellular growth and proliferation pathways. It is primarily utilized by researchers and development teams in the pharmaceutical, biotechnology, and academic sectors for drug discovery, enzyme inhibition studies, and as a reference standard.

Application

• Biochemical Research: Used as a key reagent in studies of polyamine metabolism and enzyme kinetics.
• Pharmaceutical R&D: Serves as a lead compound or reference standard in the development of novel therapeutic agents targeting cancer and parasitic diseases.
• Enzyme Inhibition Studies: Acts as a potent inhibitor of enzymes like spermidine synthase, facilitating mechanistic studies.
• Cell Biology: Employed to modulate intracellular polyamine levels to study their role in cell growth, differentiation, and apoptosis.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances.
• Academic Research: Fundamental tool in university and institutional labs for exploring polyamine function in various biological systems.

Basic Information

Product Name	N',N''-Diethylnorspermine Tetrahydrochloride
CAS No.	121749-39-1
Molecular Formula	C10H30N4 • 4HCl
Molecular Weight	363.21 g/mol (Free base: 198.33 g/mol)
Synonyms	DENSPM; Diethylnorspermine tetrahydrochloride; N1,N11-Diethylnorspermine tetrahydrochloride; 1,11-Diethyl-4,8-diazaundecane tetrahydrochloride; N,N'-Bis(3-aminopropyl)-1,4-diaminobutane tetrahydrochloride; BENSpm; Polyamine analogue DENSPM; NSC 696095
EINECS	Contact for details

Quality Control

Our N',N''-Diethylnorspermine Tetrahydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.