Description

8H-Imidazo[4,5-G]Quinazolin-8-One, 6-(Chloromethyl)-3,5-Dihydro-4,9-Dihydroxy-2,3-Dimethyl- (9Ci) is a sophisticated heterocyclic organic compound of significant interest in advanced chemical synthesis. This molecule matters as a key synthetic intermediate or potential pharmacophore, offering a complex fused-ring structure for developing novel active compounds. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of kinase inhibitors or other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Kinase Inhibitor Development: Its imidazoquinazoline core is a privileged structure for designing potent and selective kinase inhibitors.
• Biochemical Tool Compound: Employed in biochemical assays to study specific enzyme pathways and cellular signaling mechanisms.
• High-Value Fine Chemical Synthesis: Acts as a precursor in multi-step synthetic routes for complex, high-purity specialty chemicals.
• Academic Research: Utilized in universities and R&D labs for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Item	Detail
Product Name	8H-Imidazo[4,5-G]Quinazolin-8-One, 6-(Chloromethyl)-3,5-Dihydro-4,9-Dihydroxy-2,3-Dimethyl- (9Ci)
CAS No.	121732-17-0
Molecular Formula	C₁₃H₁₂ClN₃O₃
Molecular Weight	293.71 g/mol
Synonyms	6-(Chloromethyl)-3,5-dihydro-4,9-dihydroxy-2,3-dimethyl-8H-imidazo[4,5-g]quinazolin-8-one; 6-(Chloromethyl)-2,3-dimethyl-3,5-dihydro-4,9-dihydroxyimidazo[4,5-g]quinazolin-8(1H)-one; 121732-17-0; Imidazo[4,5-g]quinazolin-8-one, 6-(chloromethyl)-3,5-dihydro-4,9-dihydroxy-2,3-dimethyl-; 6-(Chloromethyl)-2,3-dimethyl-4,9-dihydroxy-3,5-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
EINECS	Contact for details

Quality Control

Our 8H-Imidazo[4,5-G]Quinazolin-8-One derivative is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions (e.g., nitrogen atmosphere) in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.