Description

5-Bromo-2-(tert-Butyldimethylsilyloxy)Pyrimidine is a high-value, protected pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise functionalization of the pyrimidine ring system, enabling the development of complex molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and production of active ingredients, as well as in academic and industrial R&D for creating novel materials and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, antiviral agents, and kinase inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Stille) and further functional group transformations.
• Material Science: Employed in the creation of organic electronic materials and functionalized polymers.
• Academic & Industrial R&D: A valuable reagent for exploring new synthetic methodologies and constructing heterocyclic libraries.

Basic Information

Product Name	5-Bromo-2-(tert-Butyldimethylsilyloxy)Pyrimidine
CAS No.	121519-00-4
Molecular Formula	C10H17BrN2OSi
Molecular Weight	289.25 g/mol
Synonyms	5-Bromo-2-[(1,1-dimethylethyl)dimethylsilyl]oxy]pyrimidine; 5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine; 2-(tert-Butyldimethylsilyloxy)-5-bromopyrimidine; 5-Bromo-2-O-tert-butyldimethylsilylpyrimidine; TBDMS Protected 5-Bromopyrimidin-2-ol; 5-Bromo-2-pyrimidinol TBDMS ether
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(tert-Butyldimethylsilyloxy)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.