Description

5-Bromo-2-isopropoxypyrimidine is a high-purity pyrimidine derivative, a crucial halogenated building block in advanced organic synthesis. Its value lies in its reactive bromine atom and protected oxygen functionality, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleoside & Nucleotide Chemistry: Employed in the modification and synthesis of nucleoside analogs for medicinal chemistry applications.
• Chemical Biology & Proteomics: Used as a versatile handle for bioconjugation and the development of chemical probes.

Basic Information

Product Name	5-Bromo-2-isopropoxypyrimidine
CAS No.	121487-12-5
Molecular Formula	C7H9BrN2O
Molecular Weight	217.06 g/mol
Synonyms	2-Isopropoxy-5-bromopyrimidine; 5-Bromo-2-(1-methylethoxy)pyrimidine; 5-Bromo-2-isopropoxy-pyrimidine; Pyrimidine, 5-bromo-2-(1-methylethoxy)-; 5-Bromo-2-(propan-2-yloxy)pyrimidine; 121487-12-5; 5-Br-2-iPrO-Pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-isopropoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.