Description

3,5-Dichloro-2-Fluoro-4-(1,1,2,3,3,3-Hexafluoropropoxy)Aniline is a high-value, multi-halogenated aniline derivative that serves as a critical advanced intermediate in modern organic synthesis. Its complex structure, featuring chlorine, fluorine, and a hexafluoropropoxy group, makes it indispensable for constructing sophisticated molecules with specific electronic and steric properties. This compound is primarily sought after by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where its halogenated aniline core contributes to the desired molecular alignment and electronic properties.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with enhanced chemical resistance, thermal stability, or specific surface characteristics.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex, high-performance dyes and pigments for niche technical applications.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies, cross-coupling reactions, and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	3,5-Dichloro-2-Fluoro-4-(1,1,2,3,3,3-Hexafluoropropoxy)Aniline
CAS No.	121451-05-6
Molecular Formula	C9H4Cl2F7NO
Molecular Weight	346.03 g/mol
Synonyms	4-Amino-3,5-dichloro-2-fluoro-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 2-Fluoro-3,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline; 3,5-Dichloro-2-fluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)benzenamine; 121451-05-6; Aniline, 3,5-dichloro-2-fluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)-; 4-(1,1,2,3,3,3-Hexafluoropropoxy)-3,5-dichloro-2-fluoroaniline
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2-Fluoro-4-(1,1,2,3,3,3-Hexafluoropropoxy)Aniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.