Description

Amylin (Free Acid) (Human) is a 37-amino acid peptide hormone, also known as Islet Amyloid Polypeptide (IAPP), produced by pancreatic beta cells. This high-purity reference standard is critical for metabolic research, particularly in the study of its role in glucose regulation and its co-secretion with insulin. It is an essential biochemical tool for pharmaceutical R&D, academic institutions, and diagnostic manufacturers focused on diabetes, obesity, and related metabolic disorders. CAS NO 121381-06-4.

Application

• Pharmaceutical Research & Development: Used as a reference standard in the discovery and development of novel therapeutics for type 2 diabetes and obesity.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) and other analytical methods for amylin detection.
• Academic & Basic Science Research: Fundamental studies on the physiology and pathophysiology of amylin, including its aggregation properties, receptor interactions, and effects on satiety and gastric emptying.
• In Vitro & Ex Vivo Studies: Applied in cell-based assays and tissue studies to investigate amylin's biological activity and signaling pathways.
• Quality Control & Standardization: Acts as a primary standard for the quality control of related pharmaceutical products and in-house laboratory standards.

Basic Information

Product Name	Amylin (Free Acid) (Human)
CAS No.	121381-06-4
Molecular Formula	C165H263N51O53S2
Molecular Weight	3904.4 g/mol
Synonyms	Islet Amyloid Polypeptide (IAPP); Human Amylin; Diabetes-Associated Peptide; Amylin-37; IAPP (1-37); Amylin, human; Amylin Peptide
EINECS	Contact for details

Quality Control

Our Amylin (Free Acid) (Human) is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use vials to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.