Description

Benzenamine, 4-Fluoro-2,6-Bis(1-Methylethyl)- is a high-purity, substituted aniline derivative characterized by its sterically hindered structure and fluorine atom, offering unique reactivity and stability for advanced chemical synthesis. This compound serves as a critical building block and ligand precursor in the development of sophisticated materials and active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific steric and electronic properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in creating complex amine-based structures with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine and diisopropyl groups contribute to biological activity and environmental persistence.
• Ligand for Catalysis: Serves as a precursor for bulky, electron-donating ligands in transition metal catalysis, enabling challenging cross-coupling and hydrogenation reactions.
• Material Science: Employed in the synthesis of specialty polymers, dyes, and liquid crystals, where its structure imparts specific solubility and thermal properties.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing complex organic molecules, leveraging the ortho-substitution for directed ortho-metalation or other regioselective transformations.

Basic Information

Product Name	Benzenamine, 4-Fluoro-2,6-Bis(1-Methylethyl)-
CAS No.	121286-64-4
Molecular Formula	C12H18FN
Molecular Weight	195.28 g/mol
Synonyms	4-Fluoro-2,6-diisopropylaniline; 2,6-Diisopropyl-4-fluoroaniline; 4-Fluoro-2,6-bis(1-methylethyl)benzenamine; 4-Fluoro-2,6-diisopropylphenylamine; 4-Fluoro-2,6-di-iso-propylaniline; F-DIPA; 4-F-DIPA
EINECS	Contact for details

Quality Control

Our production of Benzenamine, 4-Fluoro-2,6-Bis(1-Methylethyl)- adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.