Description

Quinazoline, 5,6,7,8-Tetrahydro-5-Methyl-, (R)- (9Ci) is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters because its stereospecific structure serves as a critical building block for creating complex, biologically active molecules with precise three-dimensional configurations. Pharmaceutical and agrochemical research organizations need it for the development of novel active pharmaceutical ingredients (APIs) and crop protection agents, where the (R)-enantiomer's specific spatial orientation is essential for target interaction and efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the synthesis of advanced, enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance activity and reduce environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric hydrogenation and other chiral induction reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and stereoselective chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of other high-value, complex fine chemicals and specialty materials.

Basic Information

Product Name	Quinazoline, 5,6,7,8-Tetrahydro-5-Methyl-, (R)- (9Ci)
CAS No.	121282-96-0
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(R)-5-Methyl-5,6,7,8-tetrahydroquinazoline; (5R)-5-Methyl-5,6,7,8-tetrahydroquinazoline; 5,6,7,8-Tetrahydro-5-methylquinazoline, (R)-; Tetrahydro-5-methylquinazoline, (R)-; (R)-5-Methyl-5,6,7,8-tetrahydroquinazoline; Quinazoline, 5,6,7,8-tetrahydro-5-methyl-, (R)-; (R)-5-Methyl-1,2,3,4-tetrahydroquinazoline (tautomeric form); 121282-96-0
EINECS	Contact for details

Quality Control

Our Quinazoline, 5,6,7,8-Tetrahydro-5-Methyl-, (R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.