Description

L-Homocysteine, Ethyl Ester (9Ci) is a protected derivative of the sulfur-containing amino acid homocysteine, specifically designed for advanced organic synthesis and biochemical research. This compound is a crucial building block for the preparation of more complex molecules, offering a reactive thiol group masked by an ethyl ester for improved stability and handling. It is primarily utilized by pharmaceutical researchers, process chemists, and fine chemical manufacturers involved in developing novel therapeutics, enzyme inhibitors, and diagnostic agents. The product is supplied with a focus on high purity and batch-to-batch consistency to meet the stringent demands of modern chemical development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates targeting cardiovascular diseases, neurological disorders, and metabolic conditions.
• Biochemical Research: Used in enzymatic studies, metabolic pathway analysis, and as a precursor for generating homocysteine thiolactone and other biologically active metabolites.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis for creating custom peptides and peptidomimetics.
• Reference Standard: Employed as an analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control in laboratories.
• Nutritional Science Studies: Used in *in vitro* models to study homocysteine metabolism, oxidative stress, and related cellular mechanisms.
• Chemical Biology Probes: Acts as a starting material for developing activity-based probes and labeling reagents to study protein function and interactions.

Basic Information

Product Name	L-Homocysteine, Ethyl Ester (9Ci)
CAS No.	121277-29-0
Molecular Formula	C7H15NO2S
Molecular Weight	177.26 g/mol
Synonyms	L-Homocysteine ethyl ester; (S)-2-Amino-4-mercaptobutanoic acid ethyl ester; Ethyl L-homocysteinate; Hcy-OEt; Homocysteine ethyl ester; 2-Amino-4-sulfanylbutanoic acid ethyl ester; (2S)-2-Amino-4-sulfanylbutanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our L-Homocysteine, Ethyl Ester (9Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with relevant regulatory frameworks for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.